Darwish 2005,2006, 2007.
| Trial name or title | Is there a role for hysteroscopic tubal occlusion of functionless hydrosalpinges prior to IVF/ICSI in modern practice? |
| Methods | Randomised controlled trial. Single academic centre in Egypt (women's Health University Center, Assiut University, Assiut Egypt) Patient recruitment from April 2004 to October 2006. Inclusion criteria: women with uni‐ or bilaterally laparoscopically‐proven functionless hydrosalpinges (a large blocked tube with lost major and minor folds) scheduled for IVF. Exclusion criteria: women with a frozen pelvis at laparoscopy or inaccessible tubes at lap or hysteroscopy. Follow‐up: HSG in the following cycle after the procedure; follow‐up procedure for pregnancy unclear. |
| Participants | Women with uni‐ or bilaterally laparoscopically‐proven functionless hydrosalpinges scheduled for IVF. Women with a frozen pelvis at laparoscopy or inaccessible tubes at lap or hysteroscopy were excluded. |
| Interventions | Laparoscopic occlusion by coagulation and incision of the isthmic part of the fallopian tube VERSUS Hysteroscopic tubal occlusion by electrocautery with a rollerball electrode (3mm) introduced by a resectoscope; after cervical priming with misoprostol 200mg. Procedures are performed under broad‐spectrum antibiotic coverage. |
| Outcomes | PRIMARY OUTCOMES:
Feasible acces
Confirmed tubal occlusion SECONDARY OUTCOMES Operative time Hospital stay Complications Pregnancy: not defined. |
| Starting date | April 2004 |
| Contact information | Atef M.M. Darwish, dept of obstetrics and gynaecology, women's Health University, P.O. Box(1), 71111 Assiut Egypt. a_darwish@mailcity.com |
| Notes | The objective of Darwish 2007 is mainly to conduct a safety study and a study to address the value of hysteroscopic tubal occlusion compared to laparoscopic tubal occlusion. This current study is stated to be only a preliminary study of which the follow‐up time was to short to detect pregnancy. Subsequent studies might report outcomes in terms of pregnancy. |