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. 2010 Jan 20;2010(1):CD002125. doi: 10.1002/14651858.CD002125.pub3

Darwish 2005,2006, 2007.

Trial name or title Is there a role for hysteroscopic tubal occlusion of functionless hydrosalpinges prior to IVF/ICSI in modern practice?
Methods Randomised controlled trial.
Single academic centre in Egypt (women's Health University  Center, Assiut University, Assiut Egypt) 
 Patient recruitment from April 2004 to October 2006.
Inclusion criteria: women with uni‐ or bilaterally laparoscopically‐proven functionless hydrosalpinges (a large blocked tube with lost major and minor folds) scheduled for IVF. 
 Exclusion criteria: women with a frozen pelvis at laparoscopy or inaccessible tubes at lap or hysteroscopy.
Follow‐up: HSG in the following cycle after the procedure; follow‐up procedure for pregnancy unclear.
Participants Women with uni‐ or bilaterally laparoscopically‐proven functionless hydrosalpinges scheduled for IVF. Women with a frozen pelvis at laparoscopy or inaccessible tubes at lap or hysteroscopy were excluded.
Interventions Laparoscopic occlusion by coagulation and incision of the isthmic part of the fallopian tube VERSUS Hysteroscopic tubal occlusion by electrocautery with a rollerball electrode (3mm) introduced by a resectoscope; after cervical priming with misoprostol 200mg.  
 Procedures are performed under broad‐spectrum antibiotic coverage. 
Outcomes PRIMARY OUTCOMES: 
 Feasible acces 
 Confirmed tubal occlusion
SECONDARY OUTCOMES 
 Operative time 
 Hospital stay 
 Complications 
 Pregnancy: not defined.
Starting date April 2004
Contact information Atef M.M. Darwish, dept of obstetrics and gynaecology, women's Health University, P.O. Box(1), 71111 Assiut Egypt. a_darwish@mailcity.com
Notes The objective of Darwish 2007 is mainly to conduct a safety study and a study to address the value of hysteroscopic tubal occlusion compared to laparoscopic tubal occlusion. This current study is stated to be only a preliminary study of which the follow‐up time was to short to detect pregnancy. Subsequent studies might report outcomes in terms of pregnancy.