Table 1.
Clinical characteristics of the study population and controls
Controls | MHD patients | |
---|---|---|
n | 12 | 19 |
Male | 6 (50) | 12 (63) |
Age, years | 42 (39–50) | 56 (45–57)* |
Disease history | ||
Myocardial infarction | 0 (0) | 0 (0) |
Hypertension | 0 (0) | 17 (89)* |
Diabetes mellitus | 0 (0) | 2 (11) |
Hypercholesterolemia | 0 (0) | 2 (11) |
NAFLD | 0 (0) | 1 (5) |
Systolic blood pressure, mm Hg | 123.1±15.6 | 143.3±28.1* |
Diastolic blood pressure, mm Hg | 81.0±12.1 | 70.8±22.6* |
Laboratory values | ||
Hemoglobin, g/L | − | 100.4±15.5 |
Parathyroid hormone, pg/mL | − | 222.3±196.1 |
Calcium, mmol/L | − | 2.3±0.2 |
Phosphorus, mmol/L | − | 1.6±0.4 |
Medication | ||
Use of CCB | − | 11 (58) |
Use of ARB | − | 2 (11) |
Use of ACEI | − | 5 (26) |
Use of β-receptor blocker | − | 10 (53) |
Use of aspirin | − | 1 (5) |
Statins | − | 6 (32) |
Weekly dose of epoetin, IU | − | 3,000 (3,000–6,000) |
Values expressed as n (%), mean ± SE, or median (IQR). * p < 0.05, compared with healthy controls. Comparisons between 2 groups were performed using the Mann-Whiteny U test. MHD, maintenance hemodialysis; NAFLD, non-alcoholic fatty liver disease; CCB, calcium-channel blocker; ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin II type 1 receptor blocker.