Table 1.
Characteristics of the Lifelines population.
| Characteristics | Lifelines population (n = 98,966) | No AF (n = 98,717 ) | Incident AF (n = 249) | P-value |
|---|---|---|---|---|
| Age (years) | 46 SD 13 | 46 SD 13 | 65 SD 10 | <0.001 |
| Sex (women) | 57,952 (58.6) | 57,871 (58.6) | 81 (32.5) | <0.001 |
| Cardiovascular risk factors | ||||
| Systolic blood pressure (mmHg) | 124 (115–135) | 124 (115–135) | 133 (123–146) | <0.001 |
| Diastolic blood pressure (mmHg) | 73 (67–80) | 73 (67–80) | 74 (69–82) | < 0.001 |
| Hypertension | 21,146 (25.5) | 21,043 (25.4) | 103 (50.2) | <0.001 |
| Diabetes mellitus | 2331 (2.4) | 2310 (2.3) | 21 (8.5) | <0.001 |
| Kidney disease | 493 (0.5) | 493 (0.5) | 0 (0.0) | 0.64 |
| Body mass index (kg/m2) | 26 SD 4 | 26 SD 4 | 29 SD 5 | <0.001 |
| Associated diseases | ||||
| Previous myocardial infarction | 972 (1.0) | 954 (1.0) | 18 (7.3) | <0.001 |
| Previous stroke | 712 (0.7) | 697 (0.7) | 15 (6.1) | <0.001 |
| Heart failure | 639 (0.7) | 627 (0.7) | 12 (5.7) | <0.001 |
| Chronic pulmonary obstructive disease | 4982 (5.1) | 4965 (5.1) | 17 (6.9) | 0.19 |
| Lifestyle components | ||||
| Physical activity | 7200 (4680 –10,260) | 7200 (4680–10,260) | 6720 (4125–10,545) | 0.45 |
| Nutritional status | 13 (12–13) | 13 (12–13) | 13 (13–13) | 0.52 |
| Sleep quality | 4 (3–6) | 4 (3–6) | 4(3–6) | 0.43 |
Numbers are represented as counts (percentage), continuous variables as mean SD or median (interquartile range). P-values for continuous variables are calculated with Wilcoxon test and for categorical data with Fisher exact test. Abbreviations: AF = Atrial Fibrillation, SD = standard deviation.