Jain 2008.
Methods | Study: prospective, randomised. Allocation: computer. Blinding: yes. | |
Participants | 120 patients: 60 P / 60 C. | |
Interventions |
Hernioplasty ATB: amoxicillin‐clavulanic acid 1.2 gr IV. MA: before incision. Control: placebo. |
|
Outcomes | IP= 1; IC= 1 | |
Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Computer generated code |
Allocation concealment (selection bias) | Low risk | Quote: "Randomization was performed by a computer‐generated code by a junior resident who was not involved in the surgery, data compilation or patient follow‐up. The same resident also prepared the antibiotic or the placebo syringes containing normal saline." |
Blinding (performance bias and detection bias) All outcomes | Low risk | Yes |
Blinding of participants and personnel (performance bias) All outcomes | Low risk | Yes |
Blinding of outcome assessment (detection bias) All outcomes | Low risk | Quote: "The surgeon who performed the operation was not allowed to follow up their patient." |