Study	Reason for exclusion
Crosignani 1991	Multi‐centre randomised controlled trial (RCT) comparing effectiveness of in vitro fertilisation (IVF) vs intrauterine insemination plus ovarian stimulation (IUI + gonadotropins) and IVF vs gamete intrafallopian transfer (GIFT). Pregnancy rate per cycle and live birth rate (LBR) per cycle were reported outcomes
Custers 2012	Couples with unexplained subfertility and intermediate prognosis of natural conception were randomly allocated to 6 months EM or immediate start with IUI‐COS: no IVF arm
Jarrell 1993	Diagnostic stratification not done; therefore number of participants with unexplained infertility is not known. Control group could include participants who underwent some form of fertility treatment while awaiting spontaneous pregnancy
Karande 1998	Diagnostic stratification not done. Study population included all categories of infertile couples. Couples with unexplained infertility were not analysed separately
Leeton 1987	Although study authors describe the study as randomised controlled trial (RCT), on closer inspection the method of allocation was found to be non‐random. Every second participant was allocated to the gamete intrafallopian transfer (GIFT) group
Raneiri 1995	No intervention of interest (gamete intrafallopian transfer (GIFT) excluded from 2011 review update)
Tanbo 1990	No intervention of interest (gamete intrafallopian transfer (GIFT) excluded from 2011 review update)
Zayed 1997	Randomisation was not genuine. Study authors describe method of randomisation as pseudo‐randomisation. Allocation of treatment was breached by participant preference. Pregnancy and live birth rate (LBR) per woman/couple has not been reported