Comparison 15. Triphasic NGM 180‐215‐250 μg and EE 35 μg versus monophasic LNG 100 μg and EE 20 μg.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Pregnancy per woman within 6 cycles	1	309	Odds Ratio (M‐H, Random, 95% CI)	3.02 [0.31, 29.35]
2 Proportion of cycles with spotting within 6 cycles	1	1650	Odds Ratio (M‐H, Random, 95% CI)	0.59 [0.42, 0.81]
3 Proportion of cycles with breakthrough bleeding within 6 cycles	1	1650	Odds Ratio (M‐H, Random, 95% CI)	1.16 [0.66, 2.04]
4 Proportion of cycles with amenorrhea within 6 cycles	1	1650	Odds Ratio (M‐H, Random, 95% CI)	0.57 [0.34, 0.96]
5 Total discontinuation within 6 cycles	1	309	Odds Ratio (M‐H, Random, 95% CI)	0.95 [0.52, 1.73]
6 Discontinuations due to adverse events within 6 cycles	1	309	Odds Ratio (M‐H, Random, 95% CI)	0.79 [0.21, 3.00]