Comparison 16. Triphasic NGM 180‐215‐250 μg and EE 35 μg versus monophasic DSG 150 μg and EE 20 μg + 5 days EE 10 μg.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Pregnancy per woman within 6 cycles	1	309	Odds Ratio (M‐H, Random, 95% CI)	7.09 [0.36, 138.46]
2 Proportion of cycles with spotting within 6 cycles	1	1679	Odds Ratio (M‐H, Random, 95% CI)	0.65 [0.47, 0.91]
3 Proportion of cycles with breakthrough bleeding within 6 cycles	1	1679	Odds Ratio (M‐H, Random, 95% CI)	0.98 [0.57, 1.68]
4 Proportion of cycles with amenorrhea within 6 cycles	1	1679	Odds Ratio (M‐H, Random, 95% CI)	0.37 [0.23, 0.60]
5 Total discontinuation within 6 cycles	1	309	Odds Ratio (M‐H, Random, 95% CI)	1.04 [0.57, 1.92]
6 Discontinuations due to adverse events within 6 cycles	1	309	Odds Ratio (M‐H, Random, 95% CI)	1.33 [0.29, 6.06]