Agarwal 2007.
Methods | Randomised parallel group design | |
Participants | Patients refractory to IV Diazepam | |
Interventions | Group A; IV Valproate 20 mg/kg loading dose @ 40 mg/min Group B; IV Phenytoin 20 mg/kg @ max. 50 mg/min after dilution with normal saline |
|
Outcomes | SE controlled, recurrence in 12 h and 24 h, mortality, left against medical advice, hypotension, respiratory depression, mild elevation of SGPT | |
Notes | Study conducted in India | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Not described |
Allocation concealment (selection bias) | Unclear risk | Not described |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Not described |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Not described |