Leppik 1983.

Methods	Randomised, placebo‐controlled, parallel group design
Participants	Adults (mean age 53 years), male 71%. Setting: University hospitals
Interventions	Arm 1 = lorazepam 2 mg IV Arm 2 = diazepam 5 mg IV One or two doses to achieve seizure control
Outcomes	Cessation of seizures after first dose Recovery at discharge Mortality in hospital Requirement for ventilatory support Complications Adverse effects Patients followed up until discharge from hospital
Notes	Study conducted in USA, multi‐centric (three centres)
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Randomly numbered identical kits
Allocation concealment (selection bias)	Low risk	Randomly numbered identical kits
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Double blinded
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Double blinded