| Methods |
Randomised parallel group design |
| Participants |
1 month to 15 years of age. |
| Interventions |
Arm 1 = midazolam 0.2 mg/kg IV
Arm 2 = lorazepam 0.1 mg/kg IV |
| Outcomes |
Cessation of seizures
Requirement for ventilatory support
Complications
Adverse effects |
| Notes |
Study conducted in USA |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Method of randomisation not described |
| Allocation concealment (selection bias) |
Unclear risk |
Not described |
| Blinding of participants and personnel (performance bias)
All outcomes |
Unclear risk |
There is no mention of 'blinding' in the abstract (full paper not found in our extensive search), but the short period of observation in this study may not be liable to bias in performance of the participants and personnel |
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
Even though there was no blinding, the outcome measures are unlikely to be susceptible to high degree of bias |
