Mehta 2007.

Methods	An open‐label, randomised controlled trial
Participants	Children, 5 months to 12 years of age, with refractory convulsive status epilepticus. Mean age in Valproate group‐36.3 months and Diazepam group‐44.5 months
Interventions	Valproate: LoadIng dose: 30 mg/kg diluted 1:1 in normal saline from 2 to 5 mins followed by infusion @ 5 mg/kg/hour continued until seizure‐free period of 6 hours was reached and then reduced @ 1 mg/kg/hour every 2 hours. Maintenance dose: 10 mg/kg IV every 8 hours Diazepam: 10 microgram/kg/min increased every 5 min by 10 mircogram/kg/min
Outcomes	Control of RSE, time interval for control, dose required to control RSE, breakthrough seizures, respiratory depression, hypotension
Notes	Study conducted in India
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Block randomisation method
Allocation concealment (selection bias)	High risk	No concealment
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Open‐label study
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Even though not blinded, outcomes such as seizure activity determination and occurrence of adverse events are unlikely to be subject to bias in detection