| Methods |
Randomised, placebo‐controlled, parallel group design |
| Participants |
Adult patients
Premonitory status
Patients given the drug at home by caregivers |
| Interventions |
Experimental = diazepam 0.2 mg/kg intrarectal
Control = placebo gel intrarectal |
| Outcomes |
Cessation of seizures
Complications
Adverse effects |
| Notes |
Study conducted in USA |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Method of randomisation not described |
| Allocation concealment (selection bias) |
Low risk |
Placebo‐controlled |
| Blinding of participants and personnel (performance bias)
All outcomes |
Low risk |
Double blind placebo‐controlled |
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
Double blind placebo‐controlled |
