Cohen 2006.
Methods | Parturients who requested epidural analgesia were randomised. | |
Participants | Inclusions: 136 parturients who requested epidural analgesia for labour pain. Exclusions: none stated. No. lost to follow‐up: 5 CSE women were removed from the study following failure to pierce the dura ‐ and presumably were replaced to leave 68 in both groups. The data from the successful women were included. |
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Interventions | Epidural: 68 women received 20 mL ropivacaine 0.04% (8 mg) with adrenaline and sufentanil 1 µg/mL (20 µg) followed by PCEA using same solution with 4 mL bolus and 10 minute lockout plus background infusion of 4 mL/hr. CSE: 68 women received ropivacaine 2 mg with sufentanil 5 µg intrathecally followed by PCEA as above. Both groups received rescue of 0.25% ropivacaine from 20 minutes if VAS > 3. |
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Outcomes | Maternal: time from first injection to maximal analgesia; the number who mobilised; the occurrence of hypotension and pruritus and the need for bladder catheterisation. Fetal bradycardia during the fist 30 minutes after block was also noted (this is not an outcome for this review). Neonatal: Apgar scores (actual scores not available). |
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Notes | USA. Abstracts only: 2004, 2004 and 2006. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Parturients "were randomized". |
Allocation concealment (selection bias) | Unclear risk | Not stated. |
Blinding (performance bias and detection bias) All outcomes | Unclear risk | Not stated. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Data for the women who completed the study were available. |
Selective reporting (reporting bias) | Low risk | The primary and secondary outcomes were reported. |
Other bias | Low risk | No other bias evident. |