Table 3. Expression of PGDS, GPX3 and Nrf-2 in the VH (ELISA).
Variables | High PM group | PM group | Control group | P* |
---|---|---|---|---|
Spherical equivalent refractive error (D) | −13.5 (−20.5 to −6.5) | −10.8 (−30 to 0) | −1.1 (−3.25 to 0) | <0.001 |
Axial length (mm) | 31.1 (1.2) | 27.6 (0.9) | 23.7 (1.0) | <0.001 |
PGDS (ng/mL) | 2,071.6 (326.6) | 2,702.4 (704.4) | 2,179.2 (271.6) | 0.001 |
GPX3 (ng/mL) | 2,659.3 (1,277.5) | 5,372.4 (1,694) | 4,209.1 (1,819.8) | 0.007 |
Nrf-2 (pg/mL) | 39.0 (11.0) | 41.8 (9.9) | 53. 7 (14.1) | 0.04 |
Refractive diopter is expressed as the mean (range) and the remaining data are expressed as the mean (standard deviation). *, one-way analysis of variance. Control group, patients with axial length <26.5 mm; PM group, PM patients with 26.5 mm < axial length <29.0 mm; high PM Group, PM patients with axial length >29.0 mm; VH, vitreous humor; PM, pathological myopia; PGDS, prostaglandin-H2 D-isomerase; GPX3, glutathione peroxidase 3; Nrf-2, nuclear factor erythroid 2-related factor.