Skip to main content
. 2020 Mar;8(5):193. doi: 10.21037/atm.2020.01.63

Table 3. Expression of PGDS, GPX3 and Nrf-2 in the VH (ELISA).

Variables High PM group PM group Control group P*
Spherical equivalent refractive error (D) −13.5 (−20.5 to −6.5) −10.8 (−30 to 0) −1.1 (−3.25 to 0) <0.001
Axial length (mm) 31.1 (1.2) 27.6 (0.9) 23.7 (1.0) <0.001
PGDS (ng/mL) 2,071.6 (326.6) 2,702.4 (704.4) 2,179.2 (271.6) 0.001
GPX3 (ng/mL) 2,659.3 (1,277.5) 5,372.4 (1,694) 4,209.1 (1,819.8) 0.007
Nrf-2 (pg/mL) 39.0 (11.0) 41.8 (9.9) 53. 7 (14.1) 0.04

Refractive diopter is expressed as the mean (range) and the remaining data are expressed as the mean (standard deviation). *, one-way analysis of variance. Control group, patients with axial length <26.5 mm; PM group, PM patients with 26.5 mm < axial length <29.0 mm; high PM Group, PM patients with axial length >29.0 mm; VH, vitreous humor; PM, pathological myopia; PGDS, prostaglandin-H2 D-isomerase; GPX3, glutathione peroxidase 3; Nrf-2, nuclear factor erythroid 2-related factor.