Table 1. Study drug schedule.

Treatment group	Day 1	Day 2	Day 3	Day 4
Fosaprepitant	Fosaprepitant 150 mg IV + Aprepitant simulation agent 125 mg + Palonosetron 0.25 mg IV + Dexamethasone 6 mg orally	Aprepitant simulation agent 80 mg orally + Dexamethasone 3.75 mg orally	Aprepitant simulation agent 80 mg orally + Dexamethasone 3.75 mg orally every 12 hours	Dexamethasone 3.75 mg orally every 12 hours
Aprepitant	Aprepitant 125 mg orally + Fosaprepitant simulation agent 150 mg IV + Palonosetron 0.25 mg IV + Dexamethasone 6mg orally	Aprepitant 80 mg orally + Dexamethasone 3.75 mg orally	Aprepitant 80 mg orally + Dexamethasone 3.75 mg orally + Dexamethasone simulation agent 3.75 mg orally	Dexamethasone 3.75 mg orally + Dexamethasone simulation agent 3.75 mg orally

IV, intravenous.