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. 2020 Mar;8(5):226. doi: 10.21037/atm.2020.01.08

Table 4. Associations between risk factors and bone density in men older than 50 years and postmenopausal women.

Variables Osteopenia (LG1) Osteoporosis (LG2)
Lumbar spine, aOR (95% CI) Femoral neck, aOR (95% CI) Total hips, aOR (95% CI) Lumbar spine, aOR (95% CI) Femoral neck, aOR (95% CI) Total hips, aOR (95% CI)
Age 1.05 (1.02–1.09) 1.05 (1.03–1.08) 1.05 (1.02–1.07) 1.02 (1.00–1.04) 1.02 (1.00–1.05) 1.05 (1.02–1.08)
Gender
   Female 1.11 (0.56-2.16) 1.07 (0.60–1.87) 1.71 (1.07-2.75) 1.65 (1.06–2.57) 2.43 (1.43–4.31) 2.50 (1.26–5.35)
   Male 1 1 1 1 1 1
BMI (kg/m2)
   <18.5 4.47 (1.21–29.23) 3.09 (1.15–10.82) 4.04 (1.85-10.21) 2.03 (1.20–3.52) 2.13 (1.27–3.57) 2.08 (1.14–3.75)
   18.5–24.9 1 1 1 1 1 1
   25.0–29.9 0.68 (0.39–1.19) 0.77 (0.47–1.27) 0.41 (0.27–0.63) 0.69 (0.45–1.04) 0.31 (0.17–0.54) 0.42 (0.19–0.85)
   >30.0 1.13 (0.30–5.53) 0.32 (0.10–1.05) 0.31 (0.11–0.84) 0.48 (0.22–2.79) 0.89 (0.24–2.94) 0.26 (0.01–1.63)
Hormone use 1.01 (0.98–1.03) 1.02 (1.00–1.04) 1.00 (0.99–1.02) 1.00 (0.99–1.02) 0.99 (0.97–1.01) 0.98 (0.95–1.01)
Diabetes
   No 1 1 1 1 1 1
   Yes 1.19 (0.57–2.68) 0.59 (0.29–0.98) 0.67 (0.39-1.15) 0.83 (0.49–1.38) 1.03 (0.55–1.87) 0.93 (0.43–1.90)
Hypertension
   No 1 1 1 1 1 1
   Yes 0.75 (0.41–1.38) 1.36 (0.80–2.37) 1.78 (1.15-2.79) 1.06 (0.73–1.56) 1.26 (0.82–1.93) 1.12 (0.66–1.89)
Hyperthyroidism
   No 1 1 1 1 1 1
   Yes 0.35 (0.09–1.38) 0.76 (0.22–3.03) 0.74 (0.25–2.25) 0.93 (0.31–2.97) 1.25 (0.37–3.91) 0.28 (0.01–1.72)
Calcium intake
   No 1 1 1 1 1 1
   Yes 2.00 (0.63–6.72) 0.46 (0.16–1.24) 1.09 (0.45-2.58) 0.59 (0.23–1.41) 1.39 (0.51–3.90) 0.39 (0.09–1.52)
Vitamin D
   No 1 1 1 1 1 1
   Yes 0.78 (0.24–2.30) 1.99 (0.78–5.08) 1.07 (0.46-2.42) 2.57 (0.78–9.03) 0.94 (0.35–2.57) 2.28 (0.58–10.36)
Drinking
   Never/seldom 1 1 1 1 1 1
   Always drinking 1.09 (0.33–3.77) 0.81 (0.29–2.32) 0.67 (0.25-1.74) 0.93 (0.38–2.26) 0.36 (0.11–1.04) 1.40 (0.35–5.37)
Smoking
   Non-smoker 1 1 1 1 1 1
   Current/former smoker 0.84 (0.29–2.58) 0.63 (0.23–1.77) 3.24 (1.35-8.49) 1.03 (0.46–2.31) 4.28 (1.69–11.16) 0.69 (0.18–5.38)

aOR, adjusted odds ratio; CI, confidence interval; BMI, body mass index.