Table 3. Use of medicines.
| Parameter | Non-AKI (n=512) | AKI (n=71) | Z | P |
|---|---|---|---|---|
| Analgesics and sedatives | ||||
| Propofol (IV, mg) | 16.8±116.24 | 13.55±58.13 | 1.6629 | 0.0963 |
| Diazepam (IV, mg) | 2.19±4.89 | 1.13±3.18 | −1.6056 | 0.1084 |
| Dezocine (IV, mg) | 0.36±3.58 | 0.42±2.64 | 0.2552 | 0.7986 |
| Midazolam (IV, mL) | 2.16±11.42 | 4.45±15.97 | 2.0611 | 0.0393 |
| Remifentanil (IV, mg) | 0.04±0.35 | 0.06±0.29 | 1.5297 | 0.1261 |
| Dexmedetomidine (IV, mL) | 2.46±6.63 | 3.46±7.1 | 1.5477 | 0.1217 |
| Antibiotics | ||||
| Biapenem (IV, g) | 0.06±0.57 | 0±0 | −0.8332 | 0.4047 |
| Linezolid (IV, mg) | 31.64±420.99 | 8.45±71.21 | 0.3269 | 0.7438 |
| Meropenem (IV, g) | 1.5±6.07 | 1.68±4.91 | 2.0544 | 0.0399 |
| PSTS (IV, g) | 8.26±21.27 | 17.18±28.68 | 3.4855 | 0.0005 |
| Tigecycline (IV, mg) | 0.78±17.68 | 0 | −0.3671 | 0.7135 |
| CSSS (IV, g) | 2.97±10.27 | 6.25±13.75 | 2.7236 | 0.0065 |
| Ceftriaxone (IV, g) | 1.82±5.72 | 1.92±5.64 | 0.2401 | 0.8103 |
| Cefoxitin (IV, g) | 4.02±11.07 | 3.72±10.89 | −0.4809 | 0.6306 |
| Vancomycin (IV, g) | 0.29±1.47 | 0.2±1.23 | −0.1961 | 0.8445 |
| Imipenem (IV, g) | 0.05±0.83 | 0.28±1.7 | 1.9112 | 0.056 |
| Levofloxacin (IV, mL) | 2.54±35.57 | 2.82±23.74 | 0.7782 | 0.4364 |
| Antiepileptic drugs | ||||
| Levetiracetam (PO, g) | 0.08±0.56 | 0.04±0.25 | 0.552 | 0.581 |
| Valproate (IV, g) | 1.31±2.4 | 1.73±2.86 | 0.764 | 0.4448 |
| Contrast agents | ||||
| 32 iodixanol (IV, mL) | 10.55±54.59 | 8.45±40.52 | −0.0396 | 0.9684 |
| Iohexol (IV, mL) | 23.83±69.09 | 20.42±58.91 | 0.1478 | 0.8825 |
| Gadolinium (IV, g) | 1.35±7.06 | 1.19±3.94 | −0.0544 | 0.9566 |
| Dehydrant agents | ||||
| Mannitol (IV, mL) | 1,106.64±1,509.19 | 1,163.03±1,436.13 | 0.6946 | 0.4873 |
| Glycerin fructose (IV, mL) | 390.72±868.88 | 278.17±636.04 | −0.2796 | 0.7798 |
| Hemostatics | ||||
| Hemocoagulase Bothrops Atrox (IV, IU) | 6.88±6.23 | 6.59±4.65 | 0.0304 | 0.9757 |
| Loop diuretics | ||||
| Furosemide (IV, mg) | 5.43±27.56 | 60.99±134.91 | 7.9744 | <0.00001 |
| Torasemide (IV, mL) | 0.55±4.46 | 1.44±5.47 | 2.4809 | 0.0131 |
| Proton pump inhibitors | ||||
| Esomeprazole (IV, mg) | 15.08±65.83 | 23.66±87.00 | 0.9276 | 0.3536 |
| Omeprazole (IV, mg) | 145.08±198.15 | 171.83±196.35 | 1.3291 | 0.1838 |
| Pantoprazole (IV, mg) | 142.81±184.26 | 141.97±154.89 | 0.6239 | 0.5327 |
| Vasoactive drugs | ||||
| Dopamine (IV, mg) | 35.86±306.77 | 365.35±1,354.01 | 5.5925 | <0.00001 |
| Noradrenaline (IV, mg) | 3.45±24.3 | 43.70±113.02 | 7.6569 | <0.00001 |
| Epinephrine (IV, mg) | 0.16±0.81 | 1.66±11.29 | 2.3955 | 0.0166 |
| Vasodilators | ||||
| Diltiazem (IV, mg) | 14.16±86.68 | 25.63±89.55 | 2.4626 | 0.0138 |
| Urapidil (IV, mL) | 67.18±144.04 | 105.85±168.41 | 3.8246 | 0.0001 |
| Fasudil (IV, mg) | 38.44±118.82 | 8.45±47.89 | −1.9903 | 0.0466 |
| Nimodipine (IV, mg) | 19.55±55.44 | 27.89±66.82 | 1.3052 | 0.1918 |
Data are shown as mean ± SD. AKI, acute kidney injury; PSTS, piperacillin sodium tazobactam sodium; CSSS, cefoperazone sodium sulbactam sodium.