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| Recurrence type | No. of studies | Total (n) | Trastuzumab, recur/total | Control, recur/total | Trastuzumab vs. control, odds ratio (95% CI) | P heterogeneity, I2 | P value |
|---|---|---|---|---|---|---|---|
| Overall recurrence | 7 | 1,181 | 10/552 (1.8%) | 55/629 (8.7%) | 0.201 (0.100–0.404) | 0.479, 0.0% | <0.001 |
| Distant recurrence | 5 | 673 | 0/237 | 16/436 (3.7%) | 0.328 (0.082–1.311) | 0.589, 0.0% | 0.115 |
CI, confidence interval.
