Table 3. Results of association analysis of four significant taggers SNPs located on NFATC1 gene with post-transplant BPAR episodes using multivariable logistic regression analysis adjusted by two confounding factors (CsA/TAC usage and sirolimus administration).

SNPs	Model	OR	95% CIs	P value*
rs2290154	Additive	2.2	1.36–3.55	0.001
	Dominant	2.35	1.17–4.74	0.02
	Recessive	3.33	1.47–7.52	0.003
	HOM	1.87	0.90–3.90	0.09
	HET	5.03	1.93–13.13	0.0009
rs2304738	Additive	2.13	1.31–3.45	0.002
	Dominant	2.27	1.18–4.36	0.01
	Recessive	3.35	1.32–8.48	0.01
	HOM	1.89	0.96–3.75	0.06
	HET	4.91	1.76–13.69	0.002
rs754093	Additive	2.30	1.45–3.66	0.0004
	Dominant	2.54	1.29–4.97	0.006
	Recessive	3.64	1.60–8.27	0.002
	HOM	5.56	2.16–14.27	0.0003
	HET	1.98	0.98–4.03	0.05
rs754096	Additive	2.58	1.59–4.22	0.0001
	Dominant	3.44	1.48–7.98	0.004
	Recessive	3.28	1.61–6.68	0.001
	HOM	6.72	2.48–18.14	0.0001
	HET	2.62	1.09–6.26	0.03

*, P value less than adjusted P value (0.05/14=0.0036) was considered as statistical significant. BPAR, biopsy-proven acute rejection; SNPs, single nucleotide polymorphisms; CsA, cyclosporine A; TAC, tacrolimus; OR, odds ratio; CIs, confidential intervals.