Table 2. Partial correlation analysis of variables associated with Framingham CVD risk score.
Variables | All study subjects | DM group | |||||||
---|---|---|---|---|---|---|---|---|---|
F-score | F-score (adjusted by BMI) | F-score (adjusted by HbA1C, FPG, 2-h PG) | F-score (adjusted by LDL-C, TG) | F-Score | F-score (adjusted by BMI) | F-score (adjusted by HbA1C, FPG, 2-h PG) | F-score (adjusted by LDL-C, TG) | ||
BMI (kg/m2) | 0.222* | 0.162 | 0.111 | 0.093 | −0.077 | 0.076 | |||
HbA1C (%) | 0.304** | 0.141 | 0.082 | −0.071 | −0.166 | −0.180 | |||
FPG (mg/dL) | 0.282** | 0.226* | 0.157 | 0.081 | 0.073 | −0.003 | |||
2-h PG | 0.141 | 0.018 | −0.035 | −0.103 | −0.223 | ||||
Fasting insulin (µIU/mL) | 0.130 | 0.089 | 0.132 | 0.112 | −0.002 | 0.053 | 0.121 | 0.072 | |
Fasting C-peptide (pmol/mL) | 0.359** | 0.362** | 0.319* | 0.363** | 0.189 | 0.297* | 0.180 | 0.319* | |
HOMA-IR | 0.247* | 0.184 | 0.369** | 0.161 | 0.017 | 0.058 | 0.233 | 0.048 | |
HOMA-beta | −0.174 | −0.138 | 0.068 | −0.100 | −0.100 | 0.037 | 0.046 | 0.076 | |
LDL-C (mg/dL) | 0.092 | −0.048 | −0.019 | −0.113 | −0.216 | −0.050 | −0.012 | ||
TG (mg/dL) | 0.281** | 0.287* | 0.142 | 0.124 | 0.289* | −0.058 | |||
hs-CRP (mg/L) | 0.195 | 0.147 | 0.488** | 0.175 | −0.048 | −0.045 | 0.104 | ||
apoA (mg/L) | −0.412** | −0.270 | −0.155 | −0.282 | −0.326 | −0.274 | −0.021 | −0.242 | |
apoB (mg/L) | 0.374* | 0.145 | 0.199 | 0.138 | 0.249 | 0.020 | 0.197 | 0.042 | |
IL-1beta (pg/mL) | 0.314** | 0.331*** | 0.264* | 0.302** | 0.482*** | 0.520*** | 0.547** | 0.480*** |
r value was calculated by the simple linear and partial rank correlation analysis. Partial correlation was adjusted with BMI, HbA1C, and FPG. *, P<0.05; **, P<0.01; ***, P<0.001. BMI, body mass index; HbA1c, hemoglobin A1c; FPG, fasting plasma glucose; 2-h PG, 2-hour post-load plasma glucose after 75 g oral glucose tolerance test; HOMA-IR, homeostasis model assessment-insulin resistance; LDL-C, low density lipoprotein cholesterol; TG, Triglyceride; hs-CRP, highly sensitive C-reactive protein; IL-1β, interleukin-1 β.