Table 2. Comparison of positive results and agreement among next-generation sequencing, conventional microbiological tests and cultivation method in immunosuppressed patients with suspected infection.
Group | NGS-positivea | NGS-negative | Total no. | Kappa, agreement |
---|---|---|---|---|
CMT-positive | 34 | 2 | 36 | 0.386, 66.7% |
CMT-negative | 34 | 38 | 72 | |
Culture-positive | 27 | 2 | 29 | 0.289, 60.2% |
Culture-negative | 41 | 38 | 79 | |
Total no. | 68 | 40 | 108 |
a, positive: patients with a positive microbiological diagnosis. NGS, next-generation sequencing; CMT, conventional microbiological tests.