Table S2. Test time to results for NGS and CMT in Group I.

Patient ID	Polymicrobial infection	Test time to results (days)		CMT	Results	Specimen	Clinical diagnosis
		NGS	CMT
1	No	2	1.5	Smear and culture	Aspergillus	BAL	Pulmonary infection
2	No	2.5	2	Blood culture	Candida albicans	Plasma	Bloodstream infection
3	No	2	2.5	Blood culture	Escherichia coli	Plasma	Bloodstream infection
4	No	2	2	Blood culture	Corynebacterium	Plasma	Bloodstream infection
5	Yes	2.5	2	Smear and culture	Aspergillus, Nocardia	BAL	Pulmonary infection
6	Yes	3	2	Smear and culture, Filmarray	Candida albicans, HSV 1	BAL	Pulmonary infection
7	No	2	2.5	Blood culture	Staphylococcus aureus	Plasma	Bloodstream infection
8	Yes	3	5	Smear and culture	Aspergillus, Haemophilus parainfluenzae	BAL	Pulmonary infection
9	No	2	1.5	Culture	Pseudomonas aeruginosa	Skin secretion	Skin and soft tissue infection
10	No	1.5	2	Xpert	Mycabacterium tuberculosis	Sputum	Pulmonary infection
11	No	2	2	Blood culture	Clostridium capsulatum	Plasma	Bloodstream infection
12	Yes	2.5	3.5	Smear and culture	Candida albicans, Staphylococcus aureus, Klebsiella pneumoniae	Sputum	Pulmonary infection
13	Yes	2	4.5	Smear and culture	Aspergillus, streptococcus gordonii	BAL	Pulmonary infection
14	No	3	3	Blood culture	Candida albicans	Plasma	Hepatospenic candidiasis
15	No	1.5	2.5	Blood culture	Klebsiella pneumoniae	Plasma	Bloodstream infection
16	Yes	3	5	Smear and culture, Filmarray	Candida krusei, Influenza A	BAL	Pulmonary infection
17	No	2	3	Culture	Candida albicans	Ascitic fluid	Peritonitis
18	No	2.5	2	Blood culture	Candida krusei	Plasma	Bloodstream infection
19	No	2	1.5	Blood culture	Candida krusei	Plasma	Bloodstream infection
20	No	2	2	Culture	Candida krusei	BAL	Pulmonary infection
21	Yes	3.5	4	Culture	Candida albicans, Clostridium necrosis	Puncture fluid	Liver abscess
22	No	2.5	2	Smear and culture	Candida albicans	Sputum	Pulmonary infection
23	No	2.5	3	Smear and culture	Aspergillus	Puncture fluid	Skin and soft tissue infection
24	Yes	2.5	3.5	Smear and culture, EBV-DNA, EBV IgM	Candida albicans, EBV	BAL	Pulmonary infection
25	No	1.5	2	Blood culture	Candida albicans	Puncture fluid	Kidney abscess
26	No	3	2.5	Blood culture	Escherichia coli	Plasma	Bloodstream infection
27	Yes	2	2	Culture	Klebsiella pneumoniae, Acinetobacter baumannii	BAL	Pulmonary infection
28	Yes	2	5	Smear and culture	Aspergillus, Nocardia	BAL	Pulmonary infection
29	Yes	1.5	7	Smear and culture	Candida albicans, Klebsiella pneumoniae	BAL	Pulmonary infection
30	No	2	3	Culture	Klebsiella pneumoniae	Drainage fluid	Skin and soft tissue infection
31	Yes	2	4.5	Blood culture, CMV-DNA, CMV IgM	Staphylococcus aureus, CMV	Plasma	Bloodstream infection
32	No	1.5	3.5	Blood culture	Escherichia coli	Plasma	Bloodstream infection
33	No	2	2.5	Blood culture	Cryptococcus neoformans	Plasma	Disseminated cryptococcosis
34	Yes	2.5	5.5	Blood culture	Candida albicans, Acinetobacter baumannii	Plasma	Bloodstream infection
35	No	2.5	3.5	Blood culture	Nocardia	Puncture fluid	Liver abscess
36	Yes	2	7	Smear and culture	Enterococcus faecium, Adenovirus	BAL	Pulmonary infection