Table 1. Demographic and transplant characteristics of 73 patients of BKPyVAN and 32 patients of non-BKPyVAN.
| Parameters | BKPyVAN (n=73) | non-BKPyVAN (n=32) | Total (n=105) | P |
|---|---|---|---|---|
| Gender | 0.301 | |||
| Male (%) | 40 (54.79) | 21 (65.63) | 61 (58.10) | |
| Female (%) | 33 (45.21) | 11 (34.38) | 44 (41.90) | |
| Age (years) | 41.0 (IQR: 34.0–46.0) | 33.0 (IQR: 28.0–47.0) | 39.5 (IQR: 31.0–46.3) | 0.201 |
| ESRD etiology | 0.353 | |||
| Chronic glomerulonephritis (%) | 30 (41.10) | 16 (50.00) | 46 (43.81) | |
| IgA nephropathy (%) | 21 (28.77) | 5 (15.63) | 26 (24.76) | |
| Others (%) | 22 (30.14) | 11 (34.38) | 33 (31.43) | |
| Immunosuppressive regimen | 0.220 | |||
| Tac-MPA (%) | 72 (98.63) | 30 (93.75) | 102 (97.14) | |
| CsA-MPA (%) | 1 (1.37) | 2 (6.25) | 3 (2.86) | |
| Serum creatinine at biopsy (μmol/L) | 174.0 (IQR: 134.0–268.0) | 133.0 (IQR: 110.0–150.0) | 162.0 (IQR: 124.5–236.0) | <0.001 |
| Decoy cells count (/10HPF) | 27.0 (IQR: 10.0–45.0) | 25.0 (IQR: 12.0–43.0) | 25.5 (IQR: 11.0–45.0) | 0.503 |
| Urine BKPyV-DNA loads (copies/mL) | 1.7×109 (IQR: 5.9×107–4.8×109) | 2.1×108 (IQR: 2.0×107–1.9×109) | 1.0×109 (IQR: 5.3×107–4.2×109) | 0.052 |
| Plasma BKPyV-DNA loads (copies/mL) | 5.6×103 (IQR: 1.3×103–6.0×104) | 0 (IQR: 0–8.8×102) | 1.9×103 (IQR: 0–2.6×104) | <0.001 |
BKPyVAN, BK polyomavirus associated-nephropathy; EDSR, end stage renal disease; Tac, tacrolimus; MPA, mycophenolic acid; CsA, cyclosporine A; HPF, high power field; IQR, interquartile range.