Table 2. Basic characteristics of participants across different ALDH2 genotypes.
| Characteristics | *1/*1 (n=322) | *1/*2 and *2/*2 (n=227) | P value |
|---|---|---|---|
| Age, mean (SD), years | 59.36 (2.66) | 58.94 (2.77) | 0.075 |
| Women, n (%) | 171 (53.1) | 128 (56.4) | 0.501 |
| BMI, mean (SD) | 24.30 (3.43) | 23.82 (3.12) | 0.098 |
| Smoking#, n (%) | 108 (33.9) | 83 (36.9) | 0.523 |
| Alcohol drinking#, n (%) | 121 (37.8) | 38 (16.9) | <0.001 |
| Hypertension, n (%) | 191 (59.3) | 114 (50.2) | 0.043 |
| Diabetes, n (%) | 41 (12.7) | 32 (14.1) | 0.737 |
| Hyperlipidemia, n (%) | 157 (48.8) | 107 (47.1) | 0.774 |
| CMBs, n (%) | 73 (22.7) | 30 (13.2) | 0.007 |
| Deep/mixed | 42 (13.0) | 13 (5.7) | 0.008 |
| Lobar | 31 (9.6) | 17 (7.5) | 0.471 |
#, 5 subjects had missing data for smoking and drinking status.ALDH2, aldehyde dehydrogenase 2; SD, standard deviation; BMI, body mass index; CMBs, cerebral microbleeds.