Table S1. Analysis for ALDH2 as risk factor in participants with CMBs.
| ALDH2 (*1 vs. *2) | Univariate model | Model 1 | Model 2 | |||||
|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |||
| rs671 | 1.93 (1.21–3.06) | 0.006 | 1.91 (1.17-3.12) | 0.009 | 1.87 (1.14–3.06) | 0.013 | ||
| rs2074356 | 2.13 (1.25–3.64) | 0.004 | 2.14 (1.23,3.72) | 0.005 | 2.09 (1.20–3.65) | 0.007 | ||
| rs2238151 | 1.31 (0.57–3.03) | 0.521 | 1.23 (0.53,2.87) | 0.628 | 1.31 (0.53–3.10) | 0.532 | ||
| rs4646777 | 0.76 (0.49–1.16) | 0.201 | 0.78 (0.50,1.21) | 0.265 | 0.78 (0.50–1.22) | 0.270 | ||
Model 1 was adjusted for sex, age, BMI, smoking, and drinking; model 2 was additionally adjusted for hypertension, DM, and hyperlipidemia. ALDH2, aldehyde dehydrogenase 2; CMBs, cerebral microbleeds; OR, odds ratio; CI, confidence interval; BMI, body mass index; DM, diabetes mellitus.