Table 4.

Systemic therapy for mCSPC based on volume

	Preferred agent
	ADT + abiraterone acetate	ADT + docetaxel
Low‐volume mCSPC	×	⋯
High‐volume mCSPC	×	×

Note: High volume = 4 or more bone metastases (at least one outside of axial skeleton) or visceral (lung, liver) metastases.

Low volume = if criteria for high volume are not met.

Abbreviations: ADT, androgen deprivation therapy; mCSPC, metastatic castrate‐sensitive prostate cancer.