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. 2020 Apr 3;26:e920628-1–e920628-9. doi: 10.12659/MSM.920628

Figure 4.

Figure 4

Inhibition of SNHG5 reversed the effect of high-glucose and high-fat condition. (A) SiRNA inhibited the expression of SNHG5. (B) CCK-8 assay confirmed the effect of siRNA of SNHG5 and high-glucose and high-fat culture on NCM460 and DLD-1 (C) cell growth. (D) TUNEL assay revealed changes in apoptosis of NCM460 and DLD-1 cells. (E) The release of LDH was changed by siRNA of SNHG5 and high-glucose and high-fat conditions in NCM460 and DLD-1 cells (F). Data are shown as means±SD (* P<0.05/** P<0.01 vs. SiRNA control+HGHF or siRNA+mannitol). HGHF – high-glucose and high-fat.