ISRCTN34092919.

Trial name or title	Living well with multiple morbidity: The development and evaluation of a primary care‐based complex intervention to support patients with multiple morbidities
Methods	Exploratory cluster randomised controlled trial; patients unblinded to group allocation
Participants	Patients 30 to 65 years of age, with 2 or more long‐term conditions
Interventions	CARE Plus intervention, which includes longer consultations with general practitioner or nurse, and setting specific healthcare goals. Patients will be given a self help pack, and healthcare professionals will receive training and support Control group: usual care
Outcomes	Main outcomes: health‐related quality of life; well‐being (measured at baseline, 6 months, 12 months) Other outcomes: anxiety and depression; self efficacy; self esteem; self‐rated general health; medication compliance; patient enablement; health service utilisation
Starting date	Registered 28 November 2012
Contact information
Notes	Trial registry ISRCTN34092919