Methods |
Design: prospective cohort nested within randomized trial.
Quality assessment
Control for confounding: A.
Follow‐up: A.
Blinding: A for weight, B for length and head circumference. |
Participants |
3483 healthy, term Belarussian infants. |
Interventions |
EBF = no liquids or solids other than breast milk for >= 6 months (n = 621).
MBF = EBF for 3 months with introduction of nonbreast milk liquids or solids, or both, by 6 months (n = 2862). |
Outcomes |
Monthly weight and length gain 3‐6, 6‐9, and 9‐12 months; WAZ, LAZ, WLZ, and head circumference at 6, 9, and 12 months; death; occurrence of and hospitalization for gastrointestinal and respiratory infection; atopic eczema and recurrent wheezing in first 12 months; height, weight, adiposity, allergy symptoms and diagnoses, skin‐prick tests, dental caries, IQ, teacher's academic ratings, and parent's and teacher's assessments of behaviour at 6.5 years. |
Notes |
Outcomes analyzed using multilevel regression accounting for clustering and controlling for geographic region, urban vs rural location, parental education, family atopic history, and maternal smoking during pregnancy. |
Risk of bias |
Bias |
Authors' judgement |
Support for judgement |
Allocation concealment (selection bias) |
Unclear risk |
D ‐ Not used |