| Methods |
Cross‐over, "double‐blind" no further details, No LTFU |
| Participants |
Childhood autism (ICD‐10), ADI‐R, age 3‐12 yrs, 5 males, 1 female |
| Interventions |
Three doses each of human synthetic secretin or placebo in random order |
| Outcomes |
Visual Analogue Scale, Aberrant Behavior Checklist |
| Notes |
small sample size (n=6), VAS scale graphical data only, AbBC no change, so no data presented |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
Details provided by authors |
| Allocation concealment (selection bias) |
Low risk |
Details provided by authors |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
"Double‐blind" with no further details |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
No loss to follow‐up |
