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Synthesis of a cinchona alkaloid‐derived compound library. a) Molecular structures of previously identified autophagy inhibitor oxautin‐1, newly discovered inhibitor autoquin, and the four most abundant cinchona alkaloids. b) Synthesis of C2‐functionalised derivatives using the Borono–Minisci reaction. c) Synthesis of C3‐functionalised derivatives using selective C−H activation followed by Suzuki coupling. See Table 1 for details of the R‐groups investigated.
