Table 2.
Multivariable‐adjusted RRs (95% CI) of PD by categories of weekly alcohol intake, during entire follow‐up time, the first 10 years of follow‐up only, and excluding the first 10 years of follow‐up
| Alcohol (drinks/week) | From Recruitment | First 10 Years of Follow‐up Only* | Excluding First 10 Years of Follow‐up* | Excluding First 10 Years of Follow‐up Among Never Smokers* | |||||
|---|---|---|---|---|---|---|---|---|---|
| Cases (n = 11,009) | Age‐Adjusted RR (95% CI) | Multivariable‐Adjusted RR (95% CI)* | Cases (n = 2,133) | RR (95% CI) | Cases (n = 8,876) | RR (95% CI) | Cases (n = 4,937) | RR (95% CI) | |
| 0 to <1 | 4,678 | 1.18 (1.12, 1.25) | 1.16 (1.10, 1.22)a | 1,016 | 1.25 (1.10, 1.41)a | 3,662 | 1.13 (1.07, 1.20)a | 2,129 | 1.14 (1.06, 1.23)b |
| 1 to 2 | 2,084 | 1.00 (ref) | 1.00 (ref) | 392 | 1.00 (ref) | 1,692 | 1.00 (ref) | 983 | 1.00 (ref) |
| >2 to 6 | 2,153 | 0.96 (0.90, 1.01) | 0.97 (0.91, 1.03) | 373 | 0.92 (0.80, 1.06) | 1,780 | 0.98 (0.92, 1.05) | 1,021 | 1.01 (0.93, 1.10) |
| >6 to 14 | 1,654 | 0.91 (0.85, 0.97) | 0.94 (0.88, 1.01) | 277 | 0.86 (0.74, 1.01) | 1,377 | 0.96 (0.89, 1.03) | 653 | 0.99 (0.90, 1.34) |
| >14 | 440 | 0.94 (0.85, 1.05) | 0.99 (0.90, 1.10) | 75 | 0.93 (0.73, 1.20) | 365 | 1.01 (0.90, 1.13) | 151 | 1.13 (0.95, 1.34) |
| P trend among drinkers | P = 0.04 | P = 0.32 | P = 0.36 | P = 0.50 | P = 0.39 | ||||
*
Additionally adjusted for smoking, region, deprivation index, educational attainment, strenuous exercise, body mass index, diabetes, hypertension, heart disease, stroke, and ever HRT use.
a
P < 0.0001.
b
P = 0.001.