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. 2020 Jan 7;126(7):1460–1469. doi: 10.1002/cncr.32695

Figure 4.

Figure 4

Predictive values according to prevalence based on results from matched blood samples for methylated BCAT1/IKZF1 ctDNA and CEA (n = 131). The expected range for the prevalence of recurrence is 0.1 to 0.3.5 The thresholds are 5 ng/mL for CEA and 12.8 pg per sample for ctDNA. BCAT1 indicates branched‐chain amino acid transaminase 1; CEA, carcinoembryonic antigen; ctDNA, circulating tumor DNA; IKZF1, Ikaros family zinc‐finger 1 protein; NPV, negative predictive value; PPV, positive predictive value.