Table 4.

ORs for the Presence of Recurrence Associated With a Positive Blood Test (Quantitative Methylated BCAT1/IKZF1 ctDNA or CEA) or Late‐Stage CRC

	Univariate OR for Recurrence (95% CI)	P	Adjusted OR for Recurrence (95% CI)	P
Positive ctDNA (vs negative ctDNA)	89.3 (19.6‐407.5)	<.001	155.7 (17.9‐1360.6)	<.001
Positive CEA (vs negative CEA)	12.7 (3.4‐46.7)	<.001	2.5 (0.3‐20.6)	.407
Late‐stage (stage III or IV) CRC (vs stage I or II)	4.3 (2.1‐9.4)	<.001	4.6 (1.4‐15.5)	.013

Abbreviations: BCAT1, branched‐chain amino acid transaminase 1; CEA, carcinoembryonic antigen; CI, confidence interval; CRC, colorectal cancer; ctDNA, circulating tumor DNA; IKZF1, Ikaros family zinc‐finger 1 protein; OR, odds ratio.