Table 2.
Components of our modified prognostic scoring system: b‐MIPI, iPET, and ePET scores.
| Factors | OS | PFS | ||||||
|---|---|---|---|---|---|---|---|---|
| β‐coefficients (95% CI) | P‐value | log HR | Score | β‐coefficients (95% CI) | P‐value | log HR | Score | |
| Biological MIPI | ||||||||
| Low | 0 (reference) | 0 | 0 | 0 (reference) | 0 | 0 | ||
| Intermediate | 1·24 (0·18–8·70) | 0·828 | 0 | 0 | 1·16 (0·73–1·79) | 0·543 | 0 | 0 |
| High | 8·59 (2·05–35·90) | 0·003 | 0·840 | 0·75 | 1·91 (0·91–4·03) | 0·090 | 0·217 | 0·25 |
| Interim PET‐CT | ||||||||
| Negative | 0 (reference) | 0 | 0 | 0 (reference) | 0 | 0 | ||
| Positive | 3·74 (1·05–13·36) | 0·042 | 0·480 | 0·5 | 2·05 (1·05–4·01) | 0·035 | 0·248 | 0·25 |
| End‐of‐treatment PET | ||||||||
| Negative | 0 (reference) | <0·001 | 0 | 0 | 0 (reference) | <0·001 | 1 | 0 |
| Positive | 4·41 (1·92–10·14) | 0·551 | 0·5 | 3·45 (1·89–6·31) | 0·473 | 0·5 | ||
OS, overall survival; PFS, progression‐free survival; CI, confidence interval; HR, hazard ratio; MIPI, Mantle Cell Lymphoma International Prognostic Index; b‐MIPI, biological MIPI; PET‐CT, positron emission tomography‐computed tomography.