Figure 6.

Summary of the association of mutations in the AS2/LOB domain with the ability to form AS2 bodies and the results of complementation tests with the AS2 variants used in the present study. Amino acid residues indicated in red were tested for their importance in the formation of AS2 bodies and development of normal leaf morphology, such as establishment of adaxial–abaxial polarity and development of proximal–distal polarity. Underlined residues are conserved in many ASL members of the AS2/LOB family (see Table S1) and were required for the formation of AS2 bodies and the functions of AS2 in leaf formation.