Figure 6.

Constitutive degradation of CCR4 is unimpaired by C‐terminal truncation. (A) Constitutive internalization of CCR4 in L1.2 transfectants over a 6‐h period. Data shown are the mean ± sem of 7 independent experiments. (B) Western blot showing CCR4 degradation over the same 6‐h period in whole cell lysates from L1.2 transfectants expressing WT CCR4 and CCR4‐Δ40. The blot is representative of 5 independent experiments. (C) Densitometry analysis of receptor degradation. Data were analyzed by 2‐way ANOVA with Bonferroni's multiple comparisons