TABLE 6.

Quantitative bacterial colony counts from animal studies recovered at day 7

	Group	# of samples with recovery			Average recovery (log10 CFU)
		CIED	Envelope	Tissue	CIED	Envelope	Tissue	Average total recovery (log10 CFU)
S. aureus	Control	10/10	10/10	10/10	7.84	8.70	7.32	8.79
	Treatment	0/10	0/10	0/10	0	0	0	0
	Log reduction				7.84	8.70	7.32	8.79
S. epidermidis	Control	10/10	10/10	10/10	5.40	6.38	4.28	6.43
	Treatment	2/8	2/8	3/8	1.51	2.24	1.16	2.26
	Log reduction				3.89	4.14	3.12	4.17
MRSA	Control	10/10	10/10	10/10	8.26	8.18	9.29	9.36
	Treatment	0/10	0/10	0/10	0	0	0	0
	Log reduction				8.26	8.18	9.29	9.36
E. coli	Control	10/10	10/10	10/10	7.97	8.29	8.91	9.12
	Treatment	0/10	0/10	0/10	0	0	0	0
	Log reduction				7.97	8.29	8.91	9.12
P. aeruginosa	Control	10/10	10/10	10/10	6.61	7.48	5.62	7.55
	Treatment	0/10	0/10	0/10	0	0	0	0
	Log reduction				6.61	7.48	5.62	7.55

Note. The bold values represent those with a >3 log reduction as above.

A ≥3‐log reduction constitutes a bactericidal effect whereas a <3‐log reduction is defined as a bacteriostatic effect.