Table 2.
Product | IC50 value (μM) |
|||
---|---|---|---|---|
AChE inhibitory activity | BuChE inhibitory activity | MAO-B inhibitory activity | Antioxidant activity | |
1 | 50.58 ± 3.12 | >200 | 61.26 ± 0.79 | 13.28 ± 0.27 |
2 | 4.15 ± 1.02 | 24.92 ± 0.96 | 14.67 ± 0.78 | >100 |
3 | 80.48 ± 3.41 | >200 | 298.43 ± 5.4 | 11.78 ± 0.18 |
4 | 0.74 ± 0.06 | >200 | 383.45 ± 5.08 | 33.07 ± 1.45 |
5 | 0.48 ± 0.05 | >200 | 22.48 ± 0.22 | 5.51 ± 0.20 |
6 | 24.38 ± 1.21 | >200 | 48.59 ± 2.02 | / |
7 | 0.52 ± 0.07 | 32.92 ± 0.76 | 91.13 ± 0.70 | 2.62 ± 0.21 |
8 | 9.24 ± 0.62 | >200 | 40.62 ± 1.92 | 5.96 ± 0.14 |
9 | 0.35 ± 0.03 | >200 | 354.19 ± 5.05 | 17.17 ± 0.58 |
10 | 28.65 ± 1.44 | >200 | 493.39 ± 7.10 | 13.89 ± 0.11 |
11 | 48.24 ± 0.34 | >200 | 38.61 ± 0.42 | 11.22 ± 0.24 |
12 | 5.25 ± 0.44 | 180.91 ± 1.48 | 22.85 ± 0.73 | 1.60 ± 0.10 |
13 | 0.28 ± 0.01 | 9.91 ± 0.48 | 11.24 ± 0.72 | 5.33 ± 0.08 |
14 | 3.37 ± 0.17 | 128.33 ± 4.65 | 69.65 ± 1.26 | 5.11 ± 0.13 |
15 | 2.54 ± 0.19 | >200 | 215.22 ± 2.27 | 32.58 ± 0.42 |
16 | 4.07 ± 0.19 | >200 | >500 | 18.01 ± 0.48 |
17 | 42.26 ± 4.01 | >200 | 82.68 ± 1.31 | 29.17 ± 0.31 |
18 | 123.88 ± 2.17 | >200 | 180.34 ± 1.32 | 64.48 ± 1.29 |
19 | 36.50 ± 0.51 | >200 | 145.56 ± 1.83 | 12.56 ± 0.14 |
20 | 0.089 ± 0.01 | >200 | 149.21 ± 3.39 | 42.56 ± 2.58 |
21 | 2.38 ± 0.20 | 145.89 ± 3.05 | >500 | 5.35 ± 0.33 |
22 | 2.03 ± 0.09 | >200 | 30.27 ± 0.65 | 6.44 ± 0.12 |
23 | 25.96 ± 1.26 | >200 | 43.89 ± 1.26 | 11.94 ± 0.16 |
Donepezil | 0.059 ± 0.003 | 4.67 ± 0.16 | ||
Rasagiline | 0.104 ± 0.002 | |||
Ascorbic acid | 7.69 ± 0.10 |
Each value represents the mean ± SD (n = 3).