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. 2020 Apr 7;14:295. doi: 10.3389/fnins.2020.00295

FIGURE 1.

FIGURE 1

Elucidation of binding affinity (Kd) of Curcumin with nucleic acids using fluorescence based assay. (A) Bar graph representing the binding constant (Kd) values of Curcumin with different 1 × 1 nucleotide internal motif RNAs. (B) Bar graph showing binding affinities (Kd) of Curcumin with different expanded CGG RNAs. (C) Bar chart showing Kd values of Curcumin with various RNA and DNA controls. (D) Plot illustrates curves fitting for fluorescence binding assay of Curcumin with different 1 × 1 nucleotide internal loop RNAs. (E) Plot illustrates curves fitting for fluorescence binding assay of Curcumin with different CGG repeat containing RNAs along with different RNA and DNA controls. The Curve was fitted using two mode binding model.