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. 2020 Apr 7;7:85. doi: 10.3389/fmed.2020.00085

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Copyright © 2020 You, Zhang, Shao, He, Chen, Liu, Zhang, Liu, Jia, Sun and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative analysis of blood DN B cells from healthy controls and different groups of SLE patients. (A) Frequency of DN B cells in LN patients, non-LN patients, and healthy controls. Higher frequency of DN B cells was detected in LN patients (n = 25) than in non-LN patients (n = 32). (B) Comparison among healthy controls and SLE patients with proteinuria negative (n = 37) or positive (n = 18). Differences between groups are indicated. Differences were assessed by Mann-Whitney test.