Table 4.

Improvement in discrimination when adding preoperative laboratory factors to the base model

Model	C-index for CSS	Improvement	C-index for RFS	Improvement	C-index for OS	Improvement
Base modelsa	0.762		0.724		0.750
+ ALP	0.774	0.012	0.732	0.008	0.761	0.011
+ NLR	0.778	0.016	0.737	0.013	0.765	0.015
+ Fibrinogen	0.794	0.032	0.744	0.020	0.778	0.028

^aThe base models included tumor grade, stage, lymph node invasion, tumor size, and concomitant variant histology. ALP: alkaline phosphatase; NLR: neutrophil-to-lymphocyte ratio; CSS: cancer-specific survival; RFS: disease recurrence-free survival; OS: overall survival