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. 2018 Nov 22;7(4):140–148. doi: 10.14740/jh449w

Table 1. Reference Guide for Grading Red Blood Cell Morphology (RBC-M) /hpf (100 × oil) [19].

RBCs description Normal Occasional/rare Mild/slight +1 Moderate +2 Marked +3
Microcyte MCV 80 - 99 fL MCV 70 - 79 fL (25% smaller than nucleus of small lymphocyte) MCV 60 - 69 fL (26-49% smaller than nucleus of small lymphocyte) MCV < 60 fL (≥ 50% smaller than nucleus of small lymphocyte)
Macrocyte MCV 100 - 110 fL (25% larger than nucleus of small lymphocyte) MCV 111 - 125 fL (26-49% larger than nucleus of small lymphocyte) MCV > 125 fL (≥ 50% larger than nucleus of small lymphocyte)
Hypochromasia MCH 27 - 34 pg < 5% but present 5-15% (MCH 2 - 26 pg) 16-40% (MCH 18 - 21 pg) > 40% (MCH < 18 pg)
Polychromasia < 3% but present 3-5% 6-20% > 20%
Target cells < 5% but present 5-10% 11-25% > 25%
Oval macrocytes < 5% but present 6-20% 21-50% > 50%
Anisocytosis < 15% 15-25% 26-49% 50-89%
Poikilocytosis < 1% 1-5% 6-10% > 10%

MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin, fL: femtoliter; pg: pictogram.