Figure 10.

Long-term effects of the composite biomaterial on dermal tissue remodeling. Dermal specimens were obtained on day 21 after transplantation of dermal grafts made of either porcine type I collagen alone (P) or a mixture of 55% porcine collagen and 45% jellyfish collagen (P + J). Wound scar tissue obtained without graft transplantation was also included as a control. They were subjected to H-E (A) and Sirius red staining (B) to evaluate dermal thickening and accumulation of collagen fibrils, respectively. The wound margins are indicated by arrowheads. Representative pictures are shown from eight wounds in each group.