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Remote para-arylation of phenylpropanoic acid derivatives.
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10 mol% Pd(OAc)2, 20 mol% Ac–Gly–OH, 1 equiv. arene, 1.5 equiv. NBE–CO2Me, 3 equiv. aryl iodide, 3 equiv. AgOAc, HFIP, 100 °C. For each entry number (in bold), data were reported as isolated yield.
