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. 2020 Apr 14;15(4):e0231350. doi: 10.1371/journal.pone.0231350

Table 1. Study and participant characteristics.

Author (year) Setting Study design Participants Primary Outcome(s) Key Findings Study Quality
N (I/C) Age (years), mean (±SD) % Female Population/ Condition
Ahmadidarrehsima et al. (2016) [38] Hospital, Iran Controlled Clinical Trial 50 (25/25) I: 56(46–60)
C: 40 (40–54)
100% Breast Cancer Happiness ↑ Oxford Happiness Inventory score in the TB group compared to the control group immediately post intervention (62.9 vs 29.8; p<0.001). Strong
Ahrens & Wigres (2013) [3] Hospital, USA Before & After 121 (60/61) NR NR Neurological Patients Patient Satisfaction ↑ Patient satisfaction from 29.7% to 77.3% post-TB implementation. Moderate
Badaczewski et al. (2017) [40] Paediatric Care Centre, USA Cross-sectional 44 9 (6–13) 34% Asthma Patient-centered Interactions ↑ Patient-centered communication (OR = 4.97; 95% CI: 4.47–5.53) and engagement of parents during pediatric clinical encounters following TB. Weak
Bahri et al. (2018) [41] Community Health Centre, Iran RCT 66 (32/34) I: 53.5 (1.5)
C: 53.3 (1.6)
100% Post-menopausal Women Self-care Management ↑ Knowledge about self-care and self-care activities in the TB group compared to the control group 1 month after the intervention (p<0.001). Moderate
George et al. (2018) [42] Hospital, India Before & After 98 18–70 38% Type II diabetes Medication Adherence Patients in the low and medium medication adherence groups showed an improvement in medication adherence 2 months post-TB (p<0.05). Patients who were categorized in the high adherence group did not show any change after TB (that is they continued to be highly adherent). Weak
Ghiasvand et al. (2017) [43] Hospital, Iran RCT 80 (40/40) I: 24.5 (4.5)
C: 24.5 (4.5)
100% Women with Post-partum Depression Quality of Life ↑ Post-partum quality of life in the TB group compared to control group at 8-week follow-up (124.7 vs 115.0; p<0.001). Moderate
Griffey et al. (2015) [44] Emergency Department,
USA
RCT 408 (212/196) I: 36.0 (13.2)
C: 34.7 (12.8)
60% Low Health Literacy Comprehension & Satisfaction ↑ Comprehension of post-ED medications (p<0.02), self-care (p<0.03) and follow-up instructions (p<0.001) in TB patients compared to standard care post-intervention.
↔ Comprehension or patient satisfaction between groups.
Strong
Haney & Shepherd (2014) [45] Hospital, USA Prospective Cohort 23 NR NR Heart Failure (high-risk) Hospital Re-admissions ↓ 30-day re-admission rate from 18% to 13% over 6-months. Weak
Kandula et al. (2011) [46] Outpatient Clinic, USA Two-Group, Pre-Post Study 171 (58/113) I: 52.8 (9.7)
C: 56.2 (9.9)
75% Type II Diabetes Knowledge Retention ↑ Immediate recall of information in the TB + Education vs Education Only group.
↔ Compared to education only, TB + Education did not improve knowledge retention at 2-week follow-up.
Weak
Kiser et al. (2012) [47] Primary Care Centre, USA RCT 99 (67/32) I: 63 (43–84)
C: 63 (44–83)
65% COPD Inhaler Technique ↑ Inhaler technique score in the TB group compared to usual care group (mean change: 1.6 vs -0.5; p<0.001). Moderate
Liu et al. (2018) [48] Nursing Home, China RCT 260 (126/134) I: 79.2 (8.8)
C: 79.1 (9.2)
49% Older People Health Literacy ↑ Health literacy score in the TB group compared to the control group immediately post-intervention (110.1 vs 74.9; p<0.001). Strong
Mahmoudir-ad et al. (2015) [49] Outpatient Clinic, Iran Controlled Clinical Trial 70 (35/35) I: 51.8 (4.2)
C: 50.0 (5.6)
75% Type II Diabetes Self-care Management ↑ Foot self-care scores in the TB group compared to the control group at 3-month follow-up (29.3 vs 19.2; p<0.001). Moderate
Moadab et al. (2015) [50] Hospital, Iran RCT 60 (30/30) I: 25.2 (2.9)
C: 25.5 (2.7)
100% Post-Caesarean Surgery Anxiety ↓ Anxiety level scores in patients post-TB compared to control patients awaiting caesarean surgery (50.8 vs 59.4; p<0.001). Moderate
Mollazadeh & Maslakpak (2018) [51] Outpatient Clinic, Iran RCT 84 (42/42) I: 38 (12.4)
C: 41.3 (11.7)
33% Kidney Transplant Recipients Self-care Management ↑ Self-management scores in the TB group compared to the control group at 2-month follow-up (82.5 vs 74.4; p<0.001). Strong
Morony et al. (2018) [52] Telephone Call Centre, Australia RCT 637 (261/376) I: 31.1 (6.4)
C: 31.5 (6.6)
87% Telephone Health Service Users Self-care Management ↑ Confidence to act (OR = 2.44; p = 0.06) and knowledge of healthcare services (OR = 2.68; p = 0.06) in TB callers compared to control group callers. Moderate
Negarandeh et al. (2013) [53] Outpatient Clinic, Iran RCT 83 (43/40) I: 50.3 (8.5)
C: 49.1 (8.8)
46% Type II Diabetes Knowledge Retention & Medication/ Diet Adherence ↑ Mean scores of knowledge, and adherence to medication and diet in the TB group compared to the control group at 6-week follow-up (p< 0.001). Moderate
Peter et al. (2015) [54] Hospital, USA Two-Group, Pre-Post Study 469 (180/289) NR NR Heart Failure (high-risk) Comprehension & Hospital Re-admissions ↑ Patient understanding of their disease.
↓ 12% in re-admission rates for heart failure patients 1 years post-TB implementation.
Weak
Press et al. (2011) [55] Hospital, USA Prospective Cohort 42 51.7 (17.4) 73% COPD & Asthma Inhaler Technique After one round of TB, 86% of participants achieved correct inhaler use. After a second-round of TB, all participants achieved correct use. Moderate
Slater et al. (2017) [56] Emergency Department, USA Two-Group, Pre-Post Study 209 (105/104) I: 38.0 (14.0)
C: 41.0 (18.0)
68% Emergency Department Patients Knowledge Retention ↑ Retention of discharge instructions (diagnosis, medications, follow-up instructions) in the TB group compared to the control group (recall rate 82.1% vs 70.0%; p<0.05). Weak
Waszak et al. (2018) [57] Emergency Department, USA Prospective Cohort 52 NR NR Emergency Department Patients Knowledge Retention 100% of patients clearly understood how to take opioids, and 80.8% learned something new about how to take, store, or dispose of their medications safely. Weak

I = Intervention Group; C = Control Group; SD = Standard Deviation; COPD = Chronic obstructive pulmonary disease; TB = Teach-Back; NR = Not reported.

Median (Interquartile range).

Range.