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. Author manuscript; available in PMC: 2020 Apr 14.
Published in final edited form as: Biochem J. 2019 Dec 23;476(24):3817–3834. doi: 10.1042/BCJ20190743

Figure 5. Stability of C-terminal succinimides.

Figure 5.

a) Half-lives of Ac-YH(Asu), Ac-YS(Asu) and Ac-YV(Asu) at pH 6.7 and 7.4; b) Time course of formation of Ac-YHN and Ac-YHAsp-amide following incubation of Ac-YH(Asu) at pH 6.7; c) Hydrolysis of Ac-YH(Asu), Ac-YS(Asu) and Ac-YV(Asu) and resultant ratio of Asp-amide to Asn at pH 6.7 and 7.4. All samples were incubated at 37°C and each time point n=3, +/−SD. * indicates p< 0.0005