Legesse 2002.
Methods |
Design: parallel group randomized trial Duration of study: November 2000 Follow‐up: 21 days |
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Participants |
Country: Ethiopia Setting: community Number included in study: 520 Age: 2–80 years Sex: 221 male, 299 female Inclusion criteria: not reported Exclusion criteria: not reported Lost at follow‐up: 52 (11.0%) Number positive for A lumbricoides: 387 Number included in review: 387 |
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Interventions |
Treatment strategy: screening and treat all included participants
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Outcomes |
Outcomes included:Ascaris prevalence pre‐ and post‐treatment, cure rates, pre‐ and post‐treatment GM epg, ERR, adverse events Outcomes not included in review: anthelmintic efficacy for Trichuris andS mansoni |
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Notes |
Diagnostic technique: Kato‐Katz Funding support: not reported |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Quote: "A sequentially numbered list of individuals positive for Ascaris lumbricoides and/or Trichuris trichiura infections was prepared. The list was randomly divided into treatment group using random numbers obtained from a random number table." |
Allocation concealment (selection bias) | Unclear risk | Details not reported. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Different treatment schedule. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Details not reported. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | 52 (11.0%) participants lost at follow‐up and not included in analysis. |
Selective reporting (reporting bias) | Low risk | All stated outcome were reported. |
Other bias | Low risk | No other obvious source of bias. |