Speich 2014.

Methods	Design: parallel group randomized trial Duration of study: September to November 2012 Follow‐up: 18–23 days
Participants	Country: Tanzania Setting: school Number included in study: 480 Inclusion criteria: children who were positive for either T trichiura or hookworm Age: 6–14 years Sex: 247 boys, 233 women Exclusion criteria: children who had any systemic illness (e.g. clinical malaria or hepatosplenic schistosomiasis), as assessed by a medical doctor at the initial clinical assessment Lost at follow‐up: 22 (4.6%) Number positive for A lumbricoides: 309 Number included in review: 143
Interventions	Treatment strategy: screening and treat all included participants Group 1: albendazole 400 mg single dose (n = 75) Group 2: mebendazole 500 mg single dose (n = 68) Group 3: oxantel pamoate 20 mg/kg + albendazole 400 mg (not included) Group 4: oxantel pamoate 20 mg/kg (not included)
Outcomes	Outcomes included:Ascaris prevalence pre‐ and post‐treatment, cure rate, pre‐ and post‐treatment GM epg, adverse events Outcomes not included in review: oxantel pamoate, oxantel pamoate + albendazole efficacy for Ascaris, anthelminthic efficacy for T trichiura and hookworm
Notes	Diagnostic technique: Kato‐Katz Funding support: Medicor Foundation and the Swiss National Science Foundation
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "Children were randomly assigned, with the use of block sizes of four, to receive one of four treatments."
Allocation concealment (selection bias)	Unclear risk	Details not reported.
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Quote: "Children, study‐site investigators were unaware of the study‐group assignments. In the first day children were given either oxantel pamoate or identical placebo tablets. On the second day, children were administered two tablets albendazole or placebo table plus mebendazole."
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Quote: "Laboratory technicians were unaware of the treatment assignments."
Incomplete outcome data (attrition bias) All outcomes	Low risk	22 (4.6%) participants lost at follow‐up and not included in analysis.
Selective reporting (reporting bias)	Low risk	All stated outcomes were reported.
Other bias	Low risk	No obvious source of other bias.