Wen 2008.
Methods |
Design: parallel group randomized trial Duration of study: not reported Follow‐up: 30 days |
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Participants |
Country: People's Republic of China Setting: community (multicentre) Age: 6–70 years Sex: 79 male, 125 female Number included in study: 816 Inclusion criteria: faecal egg‐positive farmers and children > 6 years of age from rural areas Exclusion criteria: other diseases such as hepatic, renal, and cardiovascular diseases; and pregnant or lactating women Follow‐up: 0 (0%) Number positive for A lumbricoides: 204 Number included in review: 204 |
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Interventions |
Treatment strategy: screening and treat all included participants
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Outcomes |
Outcomes included:Ascaris prevalence pre‐ and post‐treatment, cure rates, pre‐ and post‐treatment AM epg, ERR, adverse events Outcomes not included in review: anthelmintic efficacy for Trichuris, hookworm, and Enterobius vermicularis |
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Notes |
Diagnostic technique: Kato‐Katz Funding support: World Health Organization |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Quote: "individuals confirmed with intestinal nematode infections were chosen and stratified by age, sex, and intensity of the infection, and then were randomly assigned into treatment groups." |
Allocation concealment (selection bias) | Unclear risk | Details not reported. |
Blinding of participants and personnel (performance bias) All outcomes | High risk | Treatment drugs had different appearance. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Details not reported. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | All participants included in analysis. |
Selective reporting (reporting bias) | Low risk | All stated outcomes were reported. |
Other bias | Low risk | No obvious source of other bias. |